CD40 ligand exhibits a direct antiviral effect on Herpes Simplex Virus type-1 infection via a PI3K-dependent, autophagy-independent mechanism.

Vlahava, Virginia-Maria

CD40 ligand exhibits a direct antiviral effect on Herpes Simplex Virus type-1 infection via a PI3K-dependent, autophagy-independent mechanism. [electronic resource] - Cellular signalling Jun 2015 - 1253-63 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-3913

10.1016/j.cellsig.2015.03.002 doi


Anthracenes--pharmacology
Antiviral Agents--pharmacology
Autophagy--drug effects
Autophagy-Related Protein 5
Benzylamines--pharmacology
CD40 Ligand--genetics
Cell Line, Tumor
Cell Nucleus--metabolism
Chromones--pharmacology
Herpes Simplex Virus Protein Vmw65--metabolism
Herpesvirus 1, Human--drug effects
Humans
JNK Mitogen-Activated Protein Kinases--antagonists & inhibitors
Macrolides--pharmacology
Microtubule-Associated Proteins--antagonists & inhibitors
Morpholines--pharmacology
Phosphatidylinositol 3-Kinases--metabolism
Phosphoinositide-3 Kinase Inhibitors
Quinazolines--pharmacology
RNA Interference
RNA, Small Interfering--metabolism
Signal Transduction--drug effects
Virus Replication--drug effects