Effect of CAR polymorphism on the pharmacokinetics of artemisinin in healthy Chinese subjects.

Zang, Meitong

Effect of CAR polymorphism on the pharmacokinetics of artemisinin in healthy Chinese subjects. [electronic resource] - Drug metabolism and pharmacokinetics Feb 2015 - 123-6 p. digital

Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't

1880-0920

10.1016/j.dmpk.2014.10.008 doi


Administration, Oral
Antimalarials--blood
Area Under Curve
Artemisinins--blood
China
Constitutive Androstane Receptor
Cytochrome P-450 CYP2B6--genetics
Dose-Response Relationship, Drug
Genotype
Healthy Volunteers
Humans
Male
Polymorphism, Single Nucleotide
Receptors, Cytoplasmic and Nuclear--genetics
Time Factors