An autologous endothelial cell:peripheral blood mononuclear cell assay that detects cytokine storm responses to biologics.

Reed, Daniel M

An autologous endothelial cell:peripheral blood mononuclear cell assay that detects cytokine storm responses to biologics. [electronic resource] - FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jun 2015 - 2595-602 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1530-6860

10.1096/fj.14-268144 doi


Alemtuzumab
Antibodies, Monoclonal--pharmacology
Antibodies, Monoclonal, Humanized--pharmacology
Bevacizumab
Biological Assay--methods
Biological Products--pharmacology
Cell Proliferation--drug effects
Coculture Techniques
Culture Media--pharmacology
Cytokines--metabolism
Endothelial Cells--cytology
Enzyme-Linked Immunosorbent Assay
Human Umbilical Vein Endothelial Cells--cytology
Humans
Interleukin-2--metabolism
Interleukin-6--metabolism
Interleukin-8--metabolism
Leukocytes, Mononuclear--cytology
Reproducibility of Results
Serum--chemistry
Trastuzumab
Tumor Necrosis Factor-alpha--metabolism