Mitochondrial DNA copy number is regulated by DNA methylation and demethylation of POLGA in stem and cancer cells and their differentiated progeny.

Lee, W

Mitochondrial DNA copy number is regulated by DNA methylation and demethylation of POLGA in stem and cancer cells and their differentiated progeny. [electronic resource] - Cell death & disease Feb 2015 - e1664 p. digital

Publication Type: Journal Article

2041-4889

10.1038/cddis.2015.34 doi


Ascorbic Acid--pharmacology
Azacitidine--pharmacology
Blotting, Western
Cell Differentiation--drug effects
Cell Line
Cell Line, Tumor
Chromatin Immunoprecipitation
DNA Copy Number Variations--genetics
DNA Methylation--drug effects
DNA Polymerase gamma
DNA, Mitochondrial--genetics
DNA-Directed DNA Polymerase--genetics
Humans
Immunoprecipitation
Real-Time Polymerase Chain Reaction