Safety evaluation of standardized allergen extract of Japanese cedar pollen for sublingual immunotherapy.

Mitobe, Yuko

Safety evaluation of standardized allergen extract of Japanese cedar pollen for sublingual immunotherapy. [electronic resource] - Regulatory toxicology and pharmacology : RTP Apr 2015 - 529-40 p. digital

Publication Type: Journal Article

1096-0295

10.1016/j.yrtph.2015.02.009 doi


Administration, Oral
Allergens--administration & dosage
Animals
Cell Line
Cricetinae
Cryptomeria--immunology
DNA, Bacterial--drug effects
Dose-Response Relationship, Drug
Escherichia coli--drug effects
Humans
Injections, Intradermal
Male
Micronuclei, Chromosome-Defective--chemically induced
Micronucleus Tests
Mouth Mucosa--drug effects
Mutation
No-Observed-Adverse-Effect Level
Passive Cutaneous Anaphylaxis
Pollen--immunology
Rabbits
Rats, Sprague-Dawley
Rhinitis, Allergic, Seasonal--drug therapy
Risk Assessment
Salmonella typhimurium--drug effects
Sublingual Immunotherapy--adverse effects
Time Factors