Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology.

Devalla, Harsha D

Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology. [electronic resource] - EMBO molecular medicine Apr 2015 - 394-410 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1757-4684

10.15252/emmm.201404757 doi


Atrial Fibrillation--drug therapy
Drug Delivery Systems--methods
Drug Evaluation, Preclinical--methods
G Protein-Coupled Inwardly-Rectifying Potassium Channels--antagonists & inhibitors
Gene Expression
Heart Atria--metabolism
Humans
Kv1.5 Potassium Channel--antagonists & inhibitors
Models, Biological
Myocytes, Cardiac--metabolism
Pluripotent Stem Cells--metabolism
Potassium Channel Blockers--pharmacology