Modeling of the human alveolar rhabdomyosarcoma Pax3-Foxo1 chromosome translocation in mouse myoblasts using CRISPR-Cas9 nuclease.

Lagutina, Irina V

Modeling of the human alveolar rhabdomyosarcoma Pax3-Foxo1 chromosome translocation in mouse myoblasts using CRISPR-Cas9 nuclease. [electronic resource] - PLoS genetics 2015 - e1004951 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1553-7404

10.1371/journal.pgen.1004951 doi


Animals
CRISPR-Cas Systems
Cell Line, Tumor
Gene Expression Regulation, Neoplastic
Humans
In Situ Hybridization, Fluorescence
Mice
Myoblasts--metabolism
Oncogene Proteins, Fusion--genetics
Paired Box Transcription Factors--genetics
RNA, Messenger--biosynthesis
Rhabdomyosarcoma, Alveolar--genetics
Translocation, Genetic--genetics