Protopanaxtriol protects against 3-nitropropionic acid-induced oxidative stress in a rat model of Huntington's disease.

Gao, Yan

Protopanaxtriol protects against 3-nitropropionic acid-induced oxidative stress in a rat model of Huntington's disease. [electronic resource] - Acta pharmacologica Sinica Mar 2015 - 311-22 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1745-7254

10.1038/aps.2014.107 doi


Animals
Antioxidants--pharmacology
Basal Ganglia--drug effects
Behavior, Animal--drug effects
Disease Models, Animal
Dose-Response Relationship, Drug
HSP70 Heat-Shock Proteins--metabolism
Heme Oxygenase (Decyclizing)--metabolism
Humans
Huntington Disease--chemically induced
Male
Mitochondria--drug effects
Motor Activity--drug effects
NAD(P)H Dehydrogenase (Quinone)--metabolism
NF-E2-Related Factor 2--metabolism
Neurons--drug effects
Neuroprotective Agents--pharmacology
Nitro Compounds
Propionates
Rats, Sprague-Dawley
Reactive Oxygen Species--metabolism
Sapogenins--pharmacology
Signal Transduction--drug effects
Time Factors
Weight Loss--drug effects