Antitumour efficacy of the selumetinib and trametinib MEK inhibitors in a combined human airway-tumour-stroma lung cancer model.

Mas, Christophe

Antitumour efficacy of the selumetinib and trametinib MEK inhibitors in a combined human airway-tumour-stroma lung cancer model. [electronic resource] - Journal of biotechnology Jul 2015 - 111-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-4863

10.1016/j.jbiotec.2015.01.012 doi


Benzimidazoles--pharmacology
Cell Proliferation--drug effects
Cells, Cultured
Drug Screening Assays, Antitumor--methods
Epithelial Cells--cytology
Fibroblasts--cytology
Humans
Lung--cytology
Lung Neoplasms--drug therapy
Models, Biological
Protein Kinase Inhibitors--pharmacology
Pyridones--pharmacology
Pyrimidinones--pharmacology
Tumor Microenvironment--drug effects