Stability of the human Hsp90-p50Cdc37 chaperone complex against nucleotides and Hsp90 inhibitors, and the influence of phosphorylation by casein kinase 2.
Olesen, Sanne H
Stability of the human Hsp90-p50Cdc37 chaperone complex against nucleotides and Hsp90 inhibitors, and the influence of phosphorylation by casein kinase 2. [electronic resource] - Molecules (Basel, Switzerland) Jan 2015 - 1643-60 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1420-3049
10.3390/molecules20011643 doi
Adenosine Diphosphate--pharmacology
Adenosine Triphosphate--metabolism
Binding Sites
Calorimetry
Casein Kinase II--metabolism
Cell Cycle Proteins--metabolism
Cell Line, Tumor
Chaperonins--metabolism
Enzyme-Linked Immunosorbent Assay
HSP90 Heat-Shock Proteins--antagonists & inhibitors
Humans
Kinetics
Models, Molecular
Nucleotides--pharmacology
Phosphorylation--drug effects
Protein Interaction Maps--drug effects
Protein Stability--drug effects
Protein Structure, Tertiary
Small Molecule Libraries--pharmacology
Thermodynamics
Stability of the human Hsp90-p50Cdc37 chaperone complex against nucleotides and Hsp90 inhibitors, and the influence of phosphorylation by casein kinase 2. [electronic resource] - Molecules (Basel, Switzerland) Jan 2015 - 1643-60 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1420-3049
10.3390/molecules20011643 doi
Adenosine Diphosphate--pharmacology
Adenosine Triphosphate--metabolism
Binding Sites
Calorimetry
Casein Kinase II--metabolism
Cell Cycle Proteins--metabolism
Cell Line, Tumor
Chaperonins--metabolism
Enzyme-Linked Immunosorbent Assay
HSP90 Heat-Shock Proteins--antagonists & inhibitors
Humans
Kinetics
Models, Molecular
Nucleotides--pharmacology
Phosphorylation--drug effects
Protein Interaction Maps--drug effects
Protein Stability--drug effects
Protein Structure, Tertiary
Small Molecule Libraries--pharmacology
Thermodynamics