SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner.

Xu, Zhu

SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner. [electronic resource] - Cell cycle (Georgetown, Tex.) 2015 - 269-76 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1551-4005

10.4161/15384101.2014.980641 doi


Adult
Aging
Cells, Cultured
DNA Breaks, Double-Stranded--radiation effects
DNA Repair--drug effects
Fibroblasts--cytology
Foreskin--cytology
Genomic Instability
Humans
Light
Male
Middle Aged
Phenanthrenes--pharmacology
Poly(ADP-ribose) Polymerase Inhibitors
Poly(ADP-ribose) Polymerases--genetics
RNA Interference
RNA, Small Interfering--metabolism
Sirtuins--genetics