VEGF-A modulates expression of inhibitory checkpoints on CD8+ T cells in tumors.

Voron, Thibault

VEGF-A modulates expression of inhibitory checkpoints on CD8+ T cells in tumors. [electronic resource] - The Journal of experimental medicine Feb 2015 - 139-48 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1540-9538

10.1084/jem.20140559 doi


Animals
CD8-Positive T-Lymphocytes--drug effects
CTLA-4 Antigen--genetics
Disease Models, Animal
Female
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Lymphocytes, Tumor-Infiltrating--drug effects
Mice
Neoplasms--genetics
Programmed Cell Death 1 Receptor--antagonists & inhibitors
Protein Binding
Receptors, Vascular Endothelial Growth Factor--metabolism
Signal Transduction--drug effects
Vascular Endothelial Growth Factor A--metabolism