Histone deacetylase 6 represents a novel drug target in the oncogenic Hedgehog signaling pathway.

Dhanyamraju, Pavan Kumar

Histone deacetylase 6 represents a novel drug target in the oncogenic Hedgehog signaling pathway. [electronic resource] - Molecular cancer therapeutics Mar 2015 - 727-39 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1538-8514

10.1158/1535-7163.MCT-14-0481 doi


Animals
Cell Line
Cell Line, Tumor
Cell Survival--genetics
Cerebellar Neoplasms--genetics
Gene Expression--genetics
Gene Expression Profiling--methods
Hedgehog Proteins--genetics
Histone Deacetylase 6
Histone Deacetylases--genetics
Kruppel-Like Transcription Factors--genetics
Medulloblastoma--genetics
Mice
Mice, Inbred C57BL
NIH 3T3 Cells
Nerve Tissue Proteins--genetics
Patched Receptors
Patched-1 Receptor
Receptors, Cell Surface--genetics
Signal Transduction--genetics
Zinc Finger Protein Gli2
Zinc Finger Protein Gli3