Influence of genetic variants in TPMT and COMT associated with cisplatin induced hearing loss in patients with cancer: two new cohorts and a meta-analysis reveal significant heterogeneity between cohorts.

Hagleitner, Melanie M

Influence of genetic variants in TPMT and COMT associated with cisplatin induced hearing loss in patients with cancer: two new cohorts and a meta-analysis reveal significant heterogeneity between cohorts. [electronic resource] - PloS one 2014 - e115869 p. digital

Publication Type: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0115869 doi


Adolescent
Adult
Antineoplastic Agents--adverse effects
Bone Neoplasms--drug therapy
Catechol O-Methyltransferase--genetics
Child
Child, Preschool
Cisplatin--adverse effects
Female
Genotype
Hearing Loss--chemically induced
Humans
Male
Methyltransferases--genetics
Netherlands
Osteosarcoma--drug therapy
Polymorphism, Single Nucleotide
Spain
Young Adult