Chloroquine potentiates temozolomide cytotoxicity by inhibiting mitochondrial autophagy in glioma cells.

Hori, Yusuke S

Chloroquine potentiates temozolomide cytotoxicity by inhibiting mitochondrial autophagy in glioma cells. [electronic resource] - Journal of neuro-oncology Mar 2015 - 11-20 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1573-7373

10.1007/s11060-014-1686-9 doi


Animals
Antimalarials--pharmacology
Antineoplastic Agents, Alkylating--pharmacology
Apoptosis--drug effects
Autophagy--drug effects
Chloroquine--pharmacology
Dacarbazine--analogs & derivatives
Drug Synergism
Glioma--drug therapy
Humans
Mitochondria--drug effects
Rats
Reactive Oxygen Species--metabolism
Temozolomide
Tumor Cells, Cultured