Potent trypanocidal curcumin analogs bearing a monoenone linker motif act on trypanosoma brucei by forming an adduct with trypanothione.

Alkhaldi, Abdulsalam A M

Potent trypanocidal curcumin analogs bearing a monoenone linker motif act on trypanosoma brucei by forming an adduct with trypanothione. [electronic resource] - Molecular pharmacology 2015 - 451-64 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1521-0111

10.1124/mol.114.096016 doi


Cell Survival--drug effects
Curcumin--analogs & derivatives
Glutathione--analogs & derivatives
Humans
Spermidine--analogs & derivatives
Trypanocidal Agents--metabolism
Trypanosoma brucei brucei--drug effects