Roundabout 4 regulates blood-tumor barrier permeability through the modulation of ZO-1, Occludin, and Claudin-5 expression.

Cai, Heng

Roundabout 4 regulates blood-tumor barrier permeability through the modulation of ZO-1, Occludin, and Claudin-5 expression. [electronic resource] - Journal of neuropathology and experimental neurology Jan 2015 - 25-37 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1554-6578

10.1097/NEN.0000000000000146 doi


Blood-Brain Barrier--metabolism
Brain Neoplasms--pathology
Capillary Permeability--genetics
Cells, Cultured
Claudin-5--metabolism
Electric Impedance
Endothelial Cells--metabolism
Gene Expression Regulation, Neoplastic--genetics
Glioma--pathology
Green Fluorescent Proteins--genetics
Humans
Intercellular Signaling Peptides and Proteins--metabolism
Matrix Metalloproteinase 9--metabolism
Nerve Tissue Proteins--metabolism
Occludin--metabolism
Receptors, Cell Surface--genetics
Signal Transduction--genetics
Tight Junction Proteins--genetics
Transendothelial and Transepithelial Migration--physiology
Zonula Occludens-1 Protein--metabolism
src-Family Kinases--metabolism
Slit Homolog 2 Protein