Synergistic effects of carboxymethyl-hexanoyl chitosan, cationic polyurethane-short branch PEI in miR122 gene delivery: accelerated differentiation of iPSCs into mature hepatocyte-like cells and improved stem cell therapy in a hepatic failure model.

Chien, Yueh

Synergistic effects of carboxymethyl-hexanoyl chitosan, cationic polyurethane-short branch PEI in miR122 gene delivery: accelerated differentiation of iPSCs into mature hepatocyte-like cells and improved stem cell therapy in a hepatic failure model. [electronic resource] - Acta biomaterialia Feb 2015 - 228-44 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1878-7568

10.1016/j.actbio.2014.11.018 doi


Animals
Cell Differentiation--drug effects
Chitosan--analogs & derivatives
Disease Models, Animal
Gene Transfer Techniques
Hepatocytes--metabolism
Heterografts
Humans
Induced Pluripotent Stem Cells--metabolism
Liver Failure--genetics
Male
Mice
Mice, Inbred BALB C
Mice, Nude
MicroRNAs--biosynthesis
Polyurethanes--pharmacology