Danzhi Xiaoyao San ameliorates depressive-like behavior by shifting toward serotonin via the downregulation of hippocampal indoleamine 2,3-dioxygenase.

Zhu, Xiaoxia

Danzhi Xiaoyao San ameliorates depressive-like behavior by shifting toward serotonin via the downregulation of hippocampal indoleamine 2,3-dioxygenase. [electronic resource] - Journal of ethnopharmacology Feb 2015 - 86-93 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1872-7573

10.1016/j.jep.2014.11.031 doi


Animals
Antidepressive Agents--pharmacology
Behavior, Animal--drug effects
Cytokines--blood
Down-Regulation--drug effects
Drugs, Chinese Herbal--pharmacology
Fluoxetine--pharmacology
Hippocampus--drug effects
Indoleamine-Pyrrole 2,3,-Dioxygenase--metabolism
Kynurenine--biosynthesis
Male
Motor Activity--drug effects
Rats
Serotonin--metabolism
Tryptophan--metabolism
Up-Regulation--drug effects