Invasive breast carcinoma cells from patients exhibit MenaINV- and macrophage-dependent transendothelial migration.

Pignatelli, Jeanine

Invasive breast carcinoma cells from patients exhibit MenaINV- and macrophage-dependent transendothelial migration. [electronic resource] - Science signaling Nov 2014 - ra112 p. digital

Publication Type: Journal Article

1937-9145

10.1126/scisignal.2005329 doi


Alternative Splicing
Animals
Autocrine Communication
Biomarkers, Tumor--analysis
Biopsy, Fine-Needle
Breast Neoplasms--chemistry
Cadherins--biosynthesis
Carcinoma, Ductal, Breast--chemistry
Coculture Techniques
Endothelial Cells--cytology
Exons
Female
Gene Expression Regulation, Neoplastic
Human Umbilical Vein Endothelial Cells
Humans
Macrophages--physiology
Mice
Microfilament Proteins--analysis
Molecular Targeted Therapy
Neoplasm Grading
Neoplasm Invasiveness--physiopathology
Neoplasm Proteins--analysis
Paracrine Communication
Prognosis
Protein Isoforms--analysis
RNA Interference
RNA, Messenger--biosynthesis
RNA, Neoplasm--biosynthesis
Receptor, Macrophage Colony-Stimulating Factor--physiology
Signal Transduction
Transendothelial and Transepithelial Migration--physiology
Tumor Cells, Cultured
Tumor Microenvironment