LRRK2 localizes to endosomes and interacts with clathrin-light chains to limit Rac1 activation.

Schreij, Andrea M A

LRRK2 localizes to endosomes and interacts with clathrin-light chains to limit Rac1 activation. [electronic resource] - EMBO reports Jan 2015 - 79-86 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1469-3178

10.15252/embr.201438714 doi


Animals
Animals, Genetically Modified
Base Sequence
Brain--cytology
COS Cells
Cells, Cultured
Chlorocebus aethiops
Clathrin Light Chains--genetics
Drosophila Proteins--genetics
Drosophila melanogaster--genetics
Endosomes--metabolism
Eye--metabolism
Gene Knockdown Techniques
Humans
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
Molecular Sequence Data
Neurons--metabolism
Protein Serine-Threonine Kinases--genetics
Protein Structure, Tertiary
Rats
rac1 GTP-Binding Protein--genetics