Na+ inhibits the epithelial Na+ channel by binding to a site in an extracellular acidic cleft.
Kashlan, Ossama B
Na+ inhibits the epithelial Na+ channel by binding to a site in an extracellular acidic cleft. [electronic resource] - The Journal of biological chemistry Jan 2015 - 568-76 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1083-351X
10.1074/jbc.M114.606152 doi
Acid Sensing Ion Channels--chemistry
Action Potentials
Allosteric Regulation
Amiloride--chemistry
Amino Acid Sequence
Animals
Binding Sites
Epithelial Sodium Channel Blockers--chemistry
Epithelial Sodium Channels--chemistry
Gene Expression
Ion Transport
Mice
Models, Molecular
Molecular Sequence Data
Mutation
Oocytes
Patch-Clamp Techniques
Protein Binding
Protein Structure, Secondary
Protein Structure, Tertiary
Protein Subunits--chemistry
Sequence Alignment
Sodium--chemistry
Xenopus laevis
Na+ inhibits the epithelial Na+ channel by binding to a site in an extracellular acidic cleft. [electronic resource] - The Journal of biological chemistry Jan 2015 - 568-76 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1083-351X
10.1074/jbc.M114.606152 doi
Acid Sensing Ion Channels--chemistry
Action Potentials
Allosteric Regulation
Amiloride--chemistry
Amino Acid Sequence
Animals
Binding Sites
Epithelial Sodium Channel Blockers--chemistry
Epithelial Sodium Channels--chemistry
Gene Expression
Ion Transport
Mice
Models, Molecular
Molecular Sequence Data
Mutation
Oocytes
Patch-Clamp Techniques
Protein Binding
Protein Structure, Secondary
Protein Structure, Tertiary
Protein Subunits--chemistry
Sequence Alignment
Sodium--chemistry
Xenopus laevis