Limitation of immune tolerance-inducing thymic epithelial cell development by Spi-B-mediated negative feedback regulation.

Akiyama, Nobuko

Limitation of immune tolerance-inducing thymic epithelial cell development by Spi-B-mediated negative feedback regulation. [electronic resource] - The Journal of experimental medicine Nov 2014 - 2425-38 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1540-9538

10.1084/jem.20141207 doi


Animals
Animals, Newborn
B7-1 Antigen--immunology
Blotting, Western
Cell Differentiation--genetics
Cells, Cultured
Epithelial Cells--immunology
Feedback, Physiological
Female
Gene Expression--immunology
Immune Tolerance--genetics
Male
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Knockout
Mice, Nude
Neoplasms, Experimental--genetics
Osteoprotegerin--genetics
Protein Serine-Threonine Kinases--immunology
Proto-Oncogene Proteins c-ets--genetics
RANK Ligand--immunology
Receptor Activator of Nuclear Factor-kappa B--genetics
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction--immunology
Thymus Gland--immunology
NF-kappaB-Inducing Kinase