Calcium/Ask1/MKK7/JNK2/c-Src signalling cascade mediates disruption of intestinal epithelial tight junctions by dextran sulfate sodium.

Samak, Geetha

Calcium/Ask1/MKK7/JNK2/c-Src signalling cascade mediates disruption of intestinal epithelial tight junctions by dextran sulfate sodium. [electronic resource] - The Biochemical journal Feb 2015 - 503-15 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1470-8728

10.1042/BJ20140450 doi


Animals
Caco-2 Cells
Calcium Signaling--drug effects
Dextran Sulfate--toxicity
Female
Genes, src--drug effects
Humans
Intestinal Mucosa--drug effects
MAP Kinase Kinase 7--metabolism
MAP Kinase Kinase Kinase 5--metabolism
Mice
Mice, Inbred C57BL
Mitogen-Activated Protein Kinase 9--metabolism
Signal Transduction--drug effects
Tight Junctions--drug effects