Comparing and combining biomarkers as principal surrogates for time-to-event clinical endpoints.

Gabriel, Erin E

Comparing and combining biomarkers as principal surrogates for time-to-event clinical endpoints. [electronic resource] - Statistics in medicine 02 2015 - 381-95 p. digital

Publication Type: Comparative Study; Journal Article

1097-0258

10.1002/sim.6349 doi


Biomarkers--analysis
Causality
Clinical Trials, Phase I as Topic
Clinical Trials, Phase II as Topic
Computer Simulation
Diabetes Mellitus, Type 1--drug therapy
Diabetic Nephropathies
Glomerular Filtration Rate
Glycated Hemoglobin
Humans
Likelihood Functions
Multivariate Analysis
Randomized Controlled Trials as Topic--methods
Risk Factors
Time Factors
Treatment Outcome