Cannabinoid type 1 and type 2 receptor antagonists prevent attenuation of serotonin-induced reflex apneas by dronabinol in Sprague-Dawley rats.

Calik, Michael W

Cannabinoid type 1 and type 2 receptor antagonists prevent attenuation of serotonin-induced reflex apneas by dronabinol in Sprague-Dawley rats. [electronic resource] - PloS one 2014 - e111412 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1932-6203

10.1371/journal.pone.0111412 doi


Animals
Cannabinoid Receptor Agonists--chemistry
Dronabinol--chemistry
Electromyography
Femoral Vein--pathology
Indoles--chemistry
Male
Nodose Ganglion--drug effects
Piperidines--chemistry
Pyrazoles--chemistry
Rats
Rats, Sprague-Dawley
Receptor, Cannabinoid, CB1--antagonists & inhibitors
Receptor, Cannabinoid, CB2--antagonists & inhibitors
Serotonin--administration & dosage
Sleep Apnea, Obstructive--chemically induced
Treatment Outcome