Expression of progerin in aging mouse brains reveals structural nuclear abnormalities without detectible significant alterations in gene expression, hippocampal stem cells or behavior.

Baek, Jean-Ha

Expression of progerin in aging mouse brains reveals structural nuclear abnormalities without detectible significant alterations in gene expression, hippocampal stem cells or behavior. [electronic resource] - Human molecular genetics Mar 2015 - 1305-21 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1460-2083

10.1093/hmg/ddu541 doi


Aging--genetics
Aging, Premature--genetics
Animals
Cell Differentiation
Female
Gene Expression Regulation
Hippocampus--metabolism
Image Processing, Computer-Assisted
Lamin Type A--genetics
Lamin Type B--genetics
Male
Mice
Mice, Transgenic
Neurogenesis
Neurons--metabolism
RNA, Messenger--genetics
Stem Cells--metabolism