mTORC1 Signaling in oocytes is dispensable for the survival of primordial follicles and for female fertility.

Gorre, Nagaraju

mTORC1 Signaling in oocytes is dispensable for the survival of primordial follicles and for female fertility. [electronic resource] - PloS one 2014 - e110491 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0110491 doi


Adaptor Proteins, Signal Transducing--deficiency
Animals
Carrier Proteins--genetics
Cell Cycle Proteins
Clutch Size
Enzyme Activation
Eukaryotic Initiation Factors
Female
Fertility--genetics
Gene Expression Regulation
Growth Differentiation Factor 9--genetics
Integrases--genetics
Mechanistic Target of Rapamycin Complex 1
Mice
Mice, Knockout
Multiprotein Complexes--genetics
Oocytes--cytology
Ovarian Follicle--cytology
Phosphatidylinositol 3-Kinase--genetics
Phosphoproteins--genetics
Pregnancy
Promoter Regions, Genetic
Regulatory-Associated Protein of mTOR
Ribosomal Protein S6 Kinases, 90-kDa--genetics
Signal Transduction--genetics
TOR Serine-Threonine Kinases--genetics