FLT3 and CDK4/6 inhibitors: signaling mechanisms and tumor burden in subcutaneous and orthotopic mouse models of acute myeloid leukemia.
Zhang, Yaping
FLT3 and CDK4/6 inhibitors: signaling mechanisms and tumor burden in subcutaneous and orthotopic mouse models of acute myeloid leukemia. [electronic resource] - Journal of pharmacokinetics and pharmacodynamics Dec 2014 - 675-91 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1573-8744
10.1007/s10928-014-9393-x doi
Animals
Benzothiazoles--pharmacology
Cell Line, Tumor
Cyclin-Dependent Kinase 4--antagonists & inhibitors
Cyclin-Dependent Kinase 6--antagonists & inhibitors
Disease Models, Animal
Leukemia, Myeloid, Acute--drug therapy
Mice
Niacinamide--analogs & derivatives
Phenylurea Compounds--pharmacology
Protein Kinase Inhibitors--pharmacology
Signal Transduction--drug effects
Sorafenib
Tumor Burden--drug effects
fms-Like Tyrosine Kinase 3--antagonists & inhibitors
FLT3 and CDK4/6 inhibitors: signaling mechanisms and tumor burden in subcutaneous and orthotopic mouse models of acute myeloid leukemia. [electronic resource] - Journal of pharmacokinetics and pharmacodynamics Dec 2014 - 675-91 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1573-8744
10.1007/s10928-014-9393-x doi
Animals
Benzothiazoles--pharmacology
Cell Line, Tumor
Cyclin-Dependent Kinase 4--antagonists & inhibitors
Cyclin-Dependent Kinase 6--antagonists & inhibitors
Disease Models, Animal
Leukemia, Myeloid, Acute--drug therapy
Mice
Niacinamide--analogs & derivatives
Phenylurea Compounds--pharmacology
Protein Kinase Inhibitors--pharmacology
Signal Transduction--drug effects
Sorafenib
Tumor Burden--drug effects
fms-Like Tyrosine Kinase 3--antagonists & inhibitors