Inflammatory monocytes promote progression of Duchenne muscular dystrophy and can be therapeutically targeted via CCR2.

Mojumdar, Kamalika

Inflammatory monocytes promote progression of Duchenne muscular dystrophy and can be therapeutically targeted via CCR2. [electronic resource] - EMBO molecular medicine Nov 2014 - 1476-92 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1757-4684

10.15252/emmm.201403967 doi


Animals
Antigens, Ly--analysis
CD11b Antigen--analysis
Chemokine CCL2--metabolism
Diaphragm--pathology
Female
Immunotherapy--methods
Male
Mesenchymal Stem Cell Transplantation
Mesenchymal Stem Cells--metabolism
Mice, Inbred C57BL
Mice, Inbred mdx
Monocytes--chemistry
Muscular Dystrophy, Duchenne--immunology
Mutant Proteins--metabolism
Receptors, CCR2--antagonists & inhibitors
Treatment Outcome