RacGTPase-activating protein 1 interacts with hepatitis C virus polymerase NS5B to regulate viral replication.

Wu, Ming-Jhan

RacGTPase-activating protein 1 interacts with hepatitis C virus polymerase NS5B to regulate viral replication. [electronic resource] - Biochemical and biophysical research communications Nov 2014 - 19-24 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1090-2104

10.1016/j.bbrc.2014.10.008 doi


Allosteric Regulation
Antiviral Agents--pharmacology
Cell Line, Tumor
Drug Discovery
Enzyme Inhibitors--pharmacology
GTPase-Activating Proteins--antagonists & inhibitors
Gene Knockdown Techniques
Genotype
HEK293 Cells
Hepacivirus--drug effects
Host-Pathogen Interactions--physiology
Humans
RNA, Small Interfering--genetics
Replicon
Viral Nonstructural Proteins--antagonists & inhibitors
Virus Replication--physiology