Tyrosine phosphorylation of NEDD4 activates its ubiquitin ligase activity.

Persaud, Avinash

Tyrosine phosphorylation of NEDD4 activates its ubiquitin ligase activity. [electronic resource] - Science signaling Oct 2014 - ra95 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1937-9145

10.1126/scisignal.2005290 doi


DNA, Complementary--genetics
Endocytosis--physiology
Endosomal Sorting Complexes Required for Transport--metabolism
Enzyme-Linked Immunosorbent Assay
Epidermal Growth Factor--metabolism
Gene Knockdown Techniques
HeLa Cells
Humans
Immunoprecipitation
Models, Molecular
Mutagenesis, Site-Directed
Nedd4 Ubiquitin Protein Ligases
Phosphorylation
Proteolysis
Real-Time Polymerase Chain Reaction
Receptor Cross-Talk--physiology
Receptor, Fibroblast Growth Factor, Type 1--metabolism
Tandem Mass Spectrometry
Tyrosine--genetics
Ubiquitin-Protein Ligases--metabolism
Ubiquitination