Neuroprotection of a novel cyclopeptide C*HSDGIC* from the cyclization of PACAP (1-5) in cellular and rodent models of retinal ganglion cell apoptosis.

Cheng, Huanhuan

Neuroprotection of a novel cyclopeptide C*HSDGIC* from the cyclization of PACAP (1-5) in cellular and rodent models of retinal ganglion cell apoptosis. [electronic resource] - PloS one 2014 - e108090 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0108090 doi


Amino Acid Sequence
Animals
Apoptosis--drug effects
Benzimidazoles--metabolism
Blotting, Western
Cell Line
Cell Survival--drug effects
Cyclization
Electroretinography
Mitochondria--drug effects
Models, Animal
Molecular Sequence Data
N-Methylaspartate--administration & dosage
Neuroprotective Agents--pharmacology
Peptides, Cyclic--chemistry
Pituitary Adenylate Cyclase-Activating Polypeptide--chemistry
Rats, Sprague-Dawley
Reactive Oxygen Species--metabolism
Retinal Ganglion Cells--cytology
Ultraviolet Rays
Vision, Ocular--drug effects