Impaired cAMP generation contributes to defective glucose-stimulated insulin secretion after long-term exposure to palmitate.

Tian, Geng

Impaired cAMP generation contributes to defective glucose-stimulated insulin secretion after long-term exposure to palmitate. [electronic resource] - Diabetes Mar 2015 - 904-15 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1939-327X

10.2337/db14-1036 doi


Animals
Calcium--metabolism
Cell Survival--drug effects
Cells, Cultured
Cyclic AMP--metabolism
Female
Glucagon-Like Peptide 1--pharmacology
Glucose--pharmacology
Insulin--metabolism
Insulin Secretion
Insulin-Secreting Cells--drug effects
Mice
Palmitic Acid--pharmacology
Real-Time Polymerase Chain Reaction
Signal Transduction--drug effects