Analgesia, enhancement of spinal morphine antinociception, and inhibition of tolerance by ultra-low dose of the α2A-adrenoceptor selective antagonist BRL44408.

Milne, Brian

Analgesia, enhancement of spinal morphine antinociception, and inhibition of tolerance by ultra-low dose of the α2A-adrenoceptor selective antagonist BRL44408. [electronic resource] - European journal of pharmacology Nov 2014 - 89-97 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1879-0712

10.1016/j.ejphar.2014.08.040 doi


Adrenergic alpha-2 Receptor Antagonists--pharmacology
Analgesia--methods
Analgesics--pharmacology
Animals
Clonidine--pharmacology
Drug Tolerance
Imidazoles--pharmacology
Injections, Spinal--methods
Male
Morphine--pharmacology
Norepinephrine--pharmacology
Pain--drug therapy
Pain Management--methods
Pain Measurement--methods
Rats
Rats, Sprague-Dawley
Receptors, Adrenergic--metabolism