Complement inhibition in cynomolgus monkeys by anti-factor d antigen-binding fragment for the treatment of an advanced form of dry age-related macular degeneration.
Loyet, Kelly M
Complement inhibition in cynomolgus monkeys by anti-factor d antigen-binding fragment for the treatment of an advanced form of dry age-related macular degeneration. [electronic resource] - The Journal of pharmacology and experimental therapeutics Dec 2014 - 527-37 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1521-0103
10.1124/jpet.114.215921 doi
Animals
Cattle
Complement C3a--antagonists & inhibitors
Complement Factor D--antagonists & inhibitors
Dose-Response Relationship, Drug
Female
Humans
Immunoglobulin Fab Fragments--administration & dosage
Intravitreal Injections
Macaca fascicularis
Macular Degeneration--blood
Male
Mice
Treatment Outcome
Complement inhibition in cynomolgus monkeys by anti-factor d antigen-binding fragment for the treatment of an advanced form of dry age-related macular degeneration. [electronic resource] - The Journal of pharmacology and experimental therapeutics Dec 2014 - 527-37 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1521-0103
10.1124/jpet.114.215921 doi
Animals
Cattle
Complement C3a--antagonists & inhibitors
Complement Factor D--antagonists & inhibitors
Dose-Response Relationship, Drug
Female
Humans
Immunoglobulin Fab Fragments--administration & dosage
Intravitreal Injections
Macaca fascicularis
Macular Degeneration--blood
Male
Mice
Treatment Outcome