Transethnic meta-analysis suggests genetic variation in the HEME pathway influences potassium response in patients treated with hydrochlorothiazide.

Del-Aguila, J L

Transethnic meta-analysis suggests genetic variation in the HEME pathway influences potassium response in patients treated with hydrochlorothiazide. [electronic resource] - The pharmacogenomics journal Apr 2015 - 153-7 p. digital

Publication Type: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1473-1150

10.1038/tpj.2014.46 doi


Black or African American--genetics
Antihypertensive Agents--therapeutic use
Bayes Theorem
Carrier Proteins--genetics
Cation Transport Proteins--genetics
Chromosomes, Human, Pair 12--genetics
Chromosomes, Human, Pair 8--genetics
Female
Genome-Wide Association Study--methods
Heme--genetics
Heme-Binding Proteins
Hemeproteins--genetics
Humans
Hydrochlorothiazide--metabolism
Hypertension--drug therapy
Hypokalemia--drug therapy
Male
Middle Aged
Mitochondrial Proteins--genetics
Polymorphism, Single Nucleotide--genetics
Potassium--metabolism
White People--genetics