Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders.
Conn, P Jeffrey
Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders. [electronic resource] - Nature reviews. Drug discovery Sep 2014 - 692-708 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review
1474-1784
10.1038/nrd4308 doi
Allosteric Regulation--drug effects
Animals
Central Nervous System Agents--chemistry
Central Nervous System Diseases--drug therapy
Drug Discovery--methods
Humans
Receptors, G-Protein-Coupled--metabolism
Treatment Outcome
Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders. [electronic resource] - Nature reviews. Drug discovery Sep 2014 - 692-708 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review
1474-1784
10.1038/nrd4308 doi
Allosteric Regulation--drug effects
Animals
Central Nervous System Agents--chemistry
Central Nervous System Diseases--drug therapy
Drug Discovery--methods
Humans
Receptors, G-Protein-Coupled--metabolism
Treatment Outcome