Elastase inhibitor AZD9668 treatment prevented progression of experimental abdominal aortic aneurysms.

Delbosc, Sandrine

Elastase inhibitor AZD9668 treatment prevented progression of experimental abdominal aortic aneurysms. [electronic resource] - Journal of vascular surgery Feb 2016 - 486-92.e1 p. digital

Publication Type: Journal Article

1097-6809

10.1016/j.jvs.2014.07.102 doi


Animals
Aorta, Abdominal--drug effects
Aortic Aneurysm, Abdominal--chemically induced
Calcium Phosphates--metabolism
Dilatation, Pathologic
Disease Models, Animal
Disease Progression
Fibrosis
Matrix Metalloproteinase 9--metabolism
Neutrophil Activation--drug effects
Pancreatic Elastase
Peroxidase--metabolism
Porphyromonas gingivalis
Pyridones--blood
Rats
Serine Proteinase Inhibitors--blood
Sulfones--blood
Tissue Culture Techniques