ACK1 tyrosine kinase interacts with histone demethylase KDM3A to regulate the mammary tumor oncogene HOXA1.

Mahajan, Kiran

ACK1 tyrosine kinase interacts with histone demethylase KDM3A to regulate the mammary tumor oncogene HOXA1. [electronic resource] - The Journal of biological chemistry Oct 2014 - 28179-91 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

1083-351X

10.1074/jbc.M114.584425 doi


Adaptor Proteins, Signal Transducing
Adaptor Proteins, Vesicular Transport--genetics
Amino Acid Sequence
Animals
Binding Sites
Cell Line, Tumor
Dasatinib
Drug Resistance, Neoplasm--drug effects
Epigenesis, Genetic
Gene Expression Regulation, Neoplastic
Genes, Reporter
Humans
Jumonji Domain-Containing Histone Demethylases--genetics
Luciferases--genetics
Mammary Glands, Human--drug effects
Methylation
Models, Molecular
Molecular Sequence Data
Neuregulin-1--genetics
Protein Binding
Protein-Tyrosine Kinases--antagonists & inhibitors
Pyrimidines--pharmacology
Receptor, ErbB-2--genetics
Signal Transduction
Tamoxifen--pharmacology
Thiazoles--pharmacology
Transcription, Genetic