Hot melt extruded amorphous solid dispersion of posaconazole with improved bioavailability: investigating drug-polymer miscibility with advanced characterisation.

Fule, Ritesh

Hot melt extruded amorphous solid dispersion of posaconazole with improved bioavailability: investigating drug-polymer miscibility with advanced characterisation. [electronic resource] - BioMed research international 2014 - 146781 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2314-6141

10.1155/2014/146781 doi


Animals
Biological Availability
Calorimetry, Differential Scanning
Drug Stability
Hot Temperature
Humans
Male
Microscopy, Atomic Force
Molecular Dynamics Simulation
Polymers--chemistry
Rats, Wistar
Solubility
Spectroscopy, Fourier Transform Infrared
Spectrum Analysis, Raman
Time Factors
Triazoles--blood
X-Ray Diffraction