Chemoselective Wittig and Michael ligations of unprotected peptidyl phosphoranes in water furnish potent inhibitors of caspase-3.

Holland-Nell, Kai

Chemoselective Wittig and Michael ligations of unprotected peptidyl phosphoranes in water furnish potent inhibitors of caspase-3. [electronic resource] - Organic letters Sep 2014 - 4428-31 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1523-7052

10.1021/ol501910x doi


Caspase 3--drug effects
Caspase Inhibitors--chemical synthesis
Molecular Structure
Oligopeptides--chemical synthesis
Phosphoranes--chemical synthesis
Water--chemistry