Evolution of oseltamivir resistance mutations in Influenza A(H1N1) and A(H3N2) viruses during selection in experimentally infected mice.

Pizzorno, Andrés

Evolution of oseltamivir resistance mutations in Influenza A(H1N1) and A(H3N2) viruses during selection in experimentally infected mice. [electronic resource] - Antimicrobial agents and chemotherapy Nov 2014 - 6398-405 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1098-6596

10.1128/AAC.02956-14 doi


Animals
Antiviral Agents--pharmacology
Base Sequence
Cell Line
Dogs
Drug Resistance, Viral--genetics
Enzyme Inhibitors--pharmacology
Evolution, Molecular
Hemagglutinins, Viral--genetics
High-Throughput Nucleotide Sequencing
Influenza A Virus, H1N1 Subtype--drug effects
Influenza A Virus, H3N2 Subtype--drug effects
Madin Darby Canine Kidney Cells
Mice
Mice, Inbred BALB C
Microbial Sensitivity Tests
Neuraminidase--genetics
Orthomyxoviridae Infections--drug therapy
Oseltamivir--pharmacology
Recombinant Proteins--biosynthesis
Selection, Genetic
Sequence Analysis, RNA
Viral Proteins--genetics