Targeting channelrhodopsin-2 to ON-bipolar cells with vitreally administered AAV Restores ON and OFF visual responses in blind mice.

Macé, Emilie

Targeting channelrhodopsin-2 to ON-bipolar cells with vitreally administered AAV Restores ON and OFF visual responses in blind mice. [electronic resource] - Molecular therapy : the journal of the American Society of Gene Therapy Jan 2015 - 7-16 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1525-0024

10.1038/mt.2014.154 doi


Animals
Behavior, Animal
Blindness--genetics
Channelrhodopsins
Dependovirus--genetics
Female
Gene Expression
Gene Transfer Techniques
Genetic Engineering
Genetic Therapy--methods
Genetic Vectors
Intravitreal Injections
Light
Mice
Mice, Inbred C57BL
Mice, Transgenic
Promoter Regions, Genetic
Retinal Bipolar Cells--metabolism
Retinal Degeneration--genetics
Retinal Ganglion Cells--metabolism
Visual Perception--genetics
Vitreous Body