Development of a robust reporter-based ADCC assay with frozen, thaw-and-use cells to measure Fc effector function of therapeutic antibodies.

Cheng, Zhijie Jey

Development of a robust reporter-based ADCC assay with frozen, thaw-and-use cells to measure Fc effector function of therapeutic antibodies. [electronic resource] - Journal of immunological methods Dec 2014 - 69-81 p. digital

Publication Type: Journal Article

1872-7905

10.1016/j.jim.2014.07.010 doi


Antibodies--immunology
Antibodies, Monoclonal--immunology
Antibodies, Monoclonal, Humanized--immunology
Antibodies, Monoclonal, Murine-Derived--immunology
Antibody-Dependent Cell Cytotoxicity--immunology
Antigens, CD20--immunology
Cell Line, Tumor
Cetuximab
Cytotoxicity Tests, Immunologic
ErbB Receptors--antagonists & inhibitors
Glycosylation
Humans
Immunoglobulin Fc Fragments--immunology
Immunoglobulin G--immunology
Jurkat Cells
MCF-7 Cells
Panitumumab
Receptors, IgG--antagonists & inhibitors
Rituximab
Trastuzumab