Rapid phenotypic and genomic change in response to therapeutic pressure in prostate cancer inferred by high content analysis of single circulating tumor cells.

Dago, Angel E

Rapid phenotypic and genomic change in response to therapeutic pressure in prostate cancer inferred by high content analysis of single circulating tumor cells. [electronic resource] - PloS one 2014 - e101777 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0101777 doi


Antineoplastic Combined Chemotherapy Protocols--therapeutic use
Chromosome Aberrations
Clonal Evolution
DNA Copy Number Variations
Genomics
Humans
Immunohistochemistry
Intracellular Space
Male
Neoplasm Metastasis
Neoplastic Cells, Circulating--metabolism
Phenotype
Prostatic Neoplasms--diagnosis
Prostatic Neoplasms, Castration-Resistant
Protein Transport
Receptors, Androgen--metabolism
Single-Cell Analysis