An Activin A/BMP2 chimera, AB215, blocks estrogen signaling via induction of ID proteins in breast cancer cells.
Jung, Jae Woo
An Activin A/BMP2 chimera, AB215, blocks estrogen signaling via induction of ID proteins in breast cancer cells. [electronic resource] - BMC cancer Jul 2014 - 549 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1471-2407
10.1186/1471-2407-14-549 doi
Activins--pharmacology
Bone Morphogenetic Protein 2--pharmacology
Breast Neoplasms--drug therapy
Cell Line, Tumor
Estrogen Receptor alpha--metabolism
Female
Humans
Inhibitor of Differentiation Proteins--genetics
MCF-7 Cells
Neoplasm Transplantation
Recombinant Fusion Proteins--pharmacokinetics
Signal Transduction--drug effects
Tamoxifen--therapeutic use
Xenograft Model Antitumor Assays
An Activin A/BMP2 chimera, AB215, blocks estrogen signaling via induction of ID proteins in breast cancer cells. [electronic resource] - BMC cancer Jul 2014 - 549 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1471-2407
10.1186/1471-2407-14-549 doi
Activins--pharmacology
Bone Morphogenetic Protein 2--pharmacology
Breast Neoplasms--drug therapy
Cell Line, Tumor
Estrogen Receptor alpha--metabolism
Female
Humans
Inhibitor of Differentiation Proteins--genetics
MCF-7 Cells
Neoplasm Transplantation
Recombinant Fusion Proteins--pharmacokinetics
Signal Transduction--drug effects
Tamoxifen--therapeutic use
Xenograft Model Antitumor Assays