Transformation of human cathelicidin LL-37 into selective, stable, and potent antimicrobial compounds.

Wang, Guangshun

Transformation of human cathelicidin LL-37 into selective, stable, and potent antimicrobial compounds. [electronic resource] - ACS chemical biology Sep 2014 - 1997-2002 p. digital

Publication Type: Letter; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1554-8937

10.1021/cb500475y doi


Amino Acid Sequence
Animals
Antimicrobial Cationic Peptides--chemistry
Catheter-Related Infections--drug therapy
Disease Models, Animal
Drug Design
Enterococcus faecium--drug effects
Humans
Hydrophobic and Hydrophilic Interactions
Male
Methicillin-Resistant Staphylococcus aureus--drug effects
Mice, Inbred C57BL
Microbial Sensitivity Tests
Molecular Sequence Data
Pseudomonas aeruginosa--drug effects
Staphylococcal Infections--drug therapy
Staphylococcus aureus--drug effects
Structure-Activity Relationship
Cathelicidins