The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells.

Hamouda, Mohamed-Amine

The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells. [electronic resource] - Oncotarget Aug 2014 - 6252-66 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1949-2553

10.18632/oncotarget.2193 doi


Antineoplastic Agents--pharmacology
Autophagy--drug effects
Bortezomib--pharmacology
Cell Line, Tumor
Drug Resistance, Neoplasm
Heat-Shock Proteins--metabolism
Humans
Molecular Chaperones
Multiple Myeloma--drug therapy
Protein Folding
Protein Serine-Threonine Kinases--metabolism