HMGB1 promotes the development of pulmonary arterial hypertension in rats.

Sadamura-Takenaka, Yukari

HMGB1 promotes the development of pulmonary arterial hypertension in rats. [electronic resource] - PloS one 2014 - e102482 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0102482 doi


Animals
Bronchoalveolar Lavage Fluid--chemistry
Chemokine CCL2--blood
DNA-Binding Proteins--metabolism
Disease Models, Animal
Endothelin-1--blood
HMGB1 Protein--blood
Hemodynamics
Hypertension, Pulmonary--physiopathology
Hypertrophy, Right Ventricular--physiopathology
Inflammation--immunology
Interleukin-1beta--blood
Male
Monocrotaline
Pulmonary Artery--physiopathology
Random Allocation
Rats
Rats, Sprague-Dawley
Tumor Necrosis Factor-alpha--blood
Vascular Resistance--physiology
Ventricular Dysfunction, Right--physiopathology